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Suggest ladies of reproductive opportunity of the opportunity hazard to your fetus and also to use productive contraception through therapy and for a minimum of one thirty day period following the previous dose.
cyclophosphamide will improve the degree or result of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.
elvitegravir/cobicistat/emtricitabine/tenofovir DF raises levels of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Females who have the ability to come to be pregnant really should use helpful birth Handle (contraceptive) through treatment with AROMASIN and for 1 month soon after your last dose of AROMASIN. Tell your health care provider immediately in case you come to be pregnant or Feel you may be pregnant.
drospirenone will boost the amount or outcome of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
Estrogens or estrogen-that contains goods, including blended oral contraceptives, shouldn't be specified concomitantly with exemestane; these medication could interfere While using the pharmacologic motion and efficacy of exemestane.
estropipate decreases effects of exemestane by pharmacodynamic antagonism. Use Warning/Monitor. Estrogens or estrogen-that contains items, together with put together oral contraceptives, shouldn't be given concomitantly with exemestane; these drugs could interfere Using the pharmacologic action and efficacy of exemestane.
Exemestane is indicated with the adjuvant remedy of postmenopausal Ladies with estrogen-receptor positive early breast most cancers that have received two to a few yrs of tamoxifen and are switched to it for completion of a total of 5 consecutive many years of adjuvant hormonal therapy.[3]
When You begin or cease taking Aromasin, your physician might have to regulate the doses of some other medicines you take consistently.
siponimod and exemestane equally increase immunosuppressive outcomes; danger of more info infection. Use Caution/Keep an eye on. Warning if coadministered on account of additive immunosuppressive results throughout this kind of therapy and in the months following administration.
Stiripentol is usually a CYP3A4 inhibitor and inducer. Keep track of CYP3A4 substrates coadministered with stiripentol for elevated or diminished consequences. CYP3A4 substrates may require dosage adjustment.
Right before taking exemestane, explain to your medical doctor or pharmacist if you are allergic to it; or In case you have another allergies. This solution may possibly comprise inactive substances, which may result in allergic reactions or other troubles. Talk with your pharmacist For additional facts.
eslicarbazepine acetate will lower the level or outcome of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. For people receiving exemestane using a powerful CYP3A4 inducer the encouraged dose of exemestane is fifty mg daily following a food.